The $20m Australian Urban Research Infrastructure Network (AURIN) project (www.aurin.org.au) began in July 2010. AURIN is developing a secure, web-based virtual environment (e-Infrastructure) - a lab-in-a-browser - offering access to diverse, distributed and extremely heterogeneous data sets together with an extensive portfolio of targeted analytical and visualization tools. This is being provisioned for Australia-wide urban and built environment researchers – itself a highly heterogeneous collection of research communities with diverse demands. This talk describes these demands and their associated needs and expectations on the e-Infrastructure and illustrates through a range of working examples how the e-Infrastructure allows inter-disciplinary research collaborations to take place. An overview of the e-Infrastructure itself will be provided and how it allows tackling these demands. Time permitting a demonstration of the systems will also be given.